Shin (1-3) -β-D-glucan Haɗin da ya ɓace daga Ƙimar Kwanciyar Kwanciya zuwa Maganin Faɗakarwa

Invasive candidiasis cuta ce ta yau da kullun mai barazanar rayuwa a cikin marasa lafiya marasa lafiya.Fahimtar ganewar asali da gaggawar magani da nufin inganta sakamako ta hanyar rage amfani da maganin fungal mara amfani ya kasance babban kalubale a cikin tsarin ICU.Zaɓin zaɓi na haƙuri akan lokaci don haka yana taka muhimmiyar rawa don ingantaccen asibiti da kulawa mai tsada.Hanyoyin da ke haɗa abubuwan haɗari na asibiti da kuma bayanan Candida colonization sun inganta ikon mu na gano irin waɗannan marasa lafiya da wuri.Yayin da ƙimar tsinkayar ƙima da ƙa'idodin tsinkaya har zuwa 95 zuwa 99%, ƙimar tsinkayar ƙima ta ragu sosai, tana tsakanin 10 zuwa 60%.Sabili da haka, idan an yi amfani da ƙima mai kyau ko ƙa'ida don jagorantar farawar maganin rigakafi, ana iya kula da marasa lafiya da yawa ba dole ba.Candida biomarkers suna nuna ƙimar tsinkaya mafi girma;duk da haka, ba su da hankali kuma don haka ba za su iya gano duk lokuta na candidiasis ba.Ƙididdigar (1-3) -β-D-glucan (BG), gwajin antigen panfungal, ana ba da shawarar azaman kayan aiki na gaba don gano cututtukan mycoses masu ɓarna a cikin haɗarin hemato-oncological marasa lafiya.Matsayinta a cikin mafi yawan yawan jama'ar ICU ya rage a fayyace shi.Ingantattun dabarun zaɓi na asibiti haɗe tare da kayan aikin dakin gwaje-gwaje ana buƙatar don kula da majinyata masu dacewa a lokacin da ya dace ta hanyar rage farashin dubawa da jiyya a matsayin ƙasa kaɗan.Sabuwar hanyar da Posteraro da abokan aiki suka gabatar a cikin fitowar da ta gabata ta Mahimmancin Kulawa ta cika waɗannan buƙatun.Ƙimar BG guda ɗaya mai kyau a cikin marasa lafiya na likita da aka shigar da su zuwa ICU tare da sepsis kuma ana tsammanin za su zauna fiye da kwanaki 5 sun riga sun rubuta takardun candidemia ta kwanaki 1 zuwa 3 tare da daidaitattun ganewar asali.Aiwatar da wannan gwajin naman gwari guda ɗaya akan zaɓaɓɓen rukunin marasa lafiya na ICU tare da kiyasin 15 zuwa 20% haɗarin haɓaka candidemia hanya ce mai ban sha'awa kuma mai yuwuwar farashi mai tsada.Idan an tabbatar da shi ta hanyar bincike na multicenter, kuma an mika shi ga marasa lafiya na tiyata a cikin babban haɗarin candidiasis mai haɗari bayan tiyatar ciki, wannan tsarin ƙaddamar da haɗari na tushen Bayesian wanda ke da nufin haɓaka ingantaccen aikin asibiti ta hanyar rage amfani da albarkatun kiwon lafiya na iya sauƙaƙa sarrafa majinyata marasa lafiya cikin haɗari. na invasive candidiasis.