Ganewar IMP mai juriya ta Carbapenem K-Saiti (Tallafin Tafiya na Layi)
Gabatarwar Samfur
Ganowar IMP mai juriya ta Carbapenem K-Set (Lateral Flow Assay) tsarin gwajin immunochromatographic ne wanda aka yi niyya don gano ingantacciyar nau'in carbapenemase irin IMP a cikin yankuna na kwayan cuta.Gwajin gwajin gwaji ne na amfani da magani wanda zai iya taimakawa wajen gano nau'in nau'in nau'in carbapenem na IMP.
Halaye
| Suna | Ganewar IMP mai juriya ta Carbapenem K-Saiti (Tallafin Tafiya na Layi) |
| Hanya | Ƙididdigar Ƙwararren Ƙwararru |
| Nau'in samfurin | Mallakan kwayoyin cuta |
| Ƙayyadaddun bayanai | 25 gwaje-gwaje/kit |
| Lokacin ganowa | 10-15 min |
| Abubuwan ganowa | Enterobacteriaceae mai jurewa Carbapenem (CRE) |
| Nau'in ganowa | IMP |
| Kwanciyar hankali | K-Set yana da ƙarfi na tsawon shekaru 2 a 2°C-30°C |
Amfani
- Mai sauri
Sami sakamako a cikin mintuna 15, kwanaki 3 kafin hanyoyin gano al'ada - Sauƙi
Mai sauƙin amfani, ma'aikatan dakin gwaje-gwaje na yau da kullun na iya aiki ba tare da horo ba - Daidaito
Babban hankali da ƙayyadaddun bayanai
Ƙarfin ganowa: 0.20 ng/ml
Iya gano mafi yawan gama-gari na IMP
- Sakamakon ilhama
Babu buƙatar lissafi, sakamakon karatun gani - Tattalin Arziki
Za'a iya jigilar samfura da adanawa a zafin daki, rage farashi
Muhimmancin gwajin CRE
Gabaɗaya, Enterobacterales sune rukuni na yau da kullun na ƙwayoyin cuta waɗanda ke haifar da cututtukan da ke da alaƙa da kiwon lafiya.Wasu Enterobacterales na iya samar da wani enzyme da ake kira carbapenemase wanda ke sa maganin rigakafi kamar carbapenems, penicillins, da cephalosporins marasa tasiri.Saboda wannan dalili, an kira CRE "bacteria na mafarki" saboda akwai 'yan maganin rigakafi, idan akwai, da aka bari don magance cututtuka da waɗannan kwayoyin ke haifar.
Bacteria daga dangin Enterobacterales, ciki har da nau'in Klebsiella da Escherichia coli, na iya haifar da carbapenemase.Ana samar da Carbapenemases sau da yawa daga kwayoyin halitta da ke kan abubuwa masu iya canzawa waɗanda zasu iya yada juriya cikin sauƙi daga ƙwayar cuta zuwa ƙwayar cuta da mutum zuwa mutum.Hakanan saboda cin zarafi na amfani da maganin rigakafi da ƙayyadaddun hanyoyin da aka ɗauka don hana yaɗuwa, matsalar CRE da ke ƙaruwa sosai tana zama barazanar rayuwa a duniya.
Yawancin lokaci, ana iya sarrafa yaduwar CRE ta:
- Kula da cututtuka na CRE
- Ware marasa lafiya tare da CRE
- Cire na'urorin likitanci masu cutarwa a cikin jiki
- Yi hankali lokacin rubuta maganin rigakafi (musamman carbapenems)
- Yin amfani da tsaftataccen dabarun bakararre don rage yaduwar kamuwa da cuta
- A bi tsarin tsaftacewa na lab
……
Gano CRE yana da babbar ƙima a cikin sarrafa watsawa.Ta hanyar gwaji da wuri, masu ba da lafiya na iya ba da ingantaccen magani ga marasa lafiya masu saurin kamuwa da CRE, kuma sun cimma nasarar kula da asibiti.
IMP irin carbapenemase
Carbapenemase yana nufin wani nau'in β-lactamase wanda zai iya aƙalla mahimmanci hydrolyze imipenem ko meropenem, ciki har da A, B, D nau'in enzymes guda uku wanda tsarin kwayoyin Ambler ya rarraba.Daga cikin su, Class B sune metallo-β-lactamases (MBLs), gami da carbapenemases kamar IMP, VIM da NDM,.IMP-nau'in carbapenemase, kuma aka sani da imipenemase metallo-beta-lactamase samar da CRE, wani nau'in nau'in MBLs ne na gama gari kuma yana daga subclass 3A.Yana iya samar da ruwa kusan dukkanin maganin rigakafi β-lactam.
Aiki
- Ƙara 5 saukad da samfurin maganin maganin
- Tsoma yankunan ƙwayoyin cuta tare da madauki na inoculation mai yuwuwa
- Saka madauki a cikin bututu
- Ƙara 50 μL zuwa S da kyau, jira minti 10-15
- Karanta sakamakon
Bayanin oda
| Samfura | Bayani | Lambar samfur |
| CPI-01 | 25 gwaje-gwaje/kit | CPI-01 |
